29,047 research outputs found

    Women's sexuality after termination of pregnancy in Hong Kong Chinese

    Get PDF
    Objective: Our aim is to determine sexuality after termination of pregnancy (TOP) in Hong Kong Chinese. Design: This was a prospective study using self-administered questionnaires given before and eight weeks after abortion. Subjects: Women over age 18 years old requesting TOP were invited to participate in the study during the period 6 December 2005 to 28 March 2006. Main outcome measures: Sexual function, couple relationship and psychological well-being like depression and post-traumatic stress disorder (PTSD) were assessed. Contraception was also reviewed. Results: No significant change in the number of women who presented with sexual dysfunctions before and after abortion. However, women reported subjective decrease in sexual functions after TOP, ranging from 9.8% for those with increased vaginal pain to 24.5% for those with decreased sexual desire. Majority of them (74.8%) suffered from at least moderate degree of post-traumatic stress symptoms and 10.2% had symptoms suggestive of the presence of a PTSD. Significant associations were seen in subjective decrease of sexual functions with post-traumatic stress symptoms after termination of pregnancy. On the other hand, 41.6% felt less depressed after abortion. There was no significant change in couple relationship after abortion. Conclusion: Termination of pregnancy did not cause sexual dysfunctions. However, significant proportion of women did suffer from decreased sexual functions subjectively which may be due to stress related to unplanned pregnancy or the TOP. The abortion itself did not cause depression and women who had completed family were less depressed after abortion. Post-traumatic stress was prevalent in those having abortion and the symptoms were associated with the subjective decrease in sexual functions.published_or_final_versio

    Streaming Algorithms for Submodular Function Maximization

    Full text link
    We consider the problem of maximizing a nonnegative submodular set function f:2NR+f:2^{\mathcal{N}} \rightarrow \mathbb{R}^+ subject to a pp-matchoid constraint in the single-pass streaming setting. Previous work in this context has considered streaming algorithms for modular functions and monotone submodular functions. The main result is for submodular functions that are {\em non-monotone}. We describe deterministic and randomized algorithms that obtain a Ω(1p)\Omega(\frac{1}{p})-approximation using O(klogk)O(k \log k)-space, where kk is an upper bound on the cardinality of the desired set. The model assumes value oracle access to ff and membership oracles for the matroids defining the pp-matchoid constraint.Comment: 29 pages, 7 figures, extended abstract to appear in ICALP 201

    Radically different maxicircle classes within the same kinetoplast: an artefact or a novel feature of the kinetoplast genome?

    Get PDF
    We discuss here some results which suggest that radically different maxicircle classes coexist within the same kinetoplast. These data, although tentative and incomplete, may provide a new outlook on the kinetoplast genome structure and expression

    Are L-myc genotypes prognostic markers in non-small cell lung carcinoma (NSCLC) in our Chinese patients?

    Get PDF
    published_or_final_versio

    Use of a sample-to-result shotgun metagenomics platform for the detection and quantification of viral pathogens in paediatric immunocompromised patients

    Get PDF
    Background: Infections by several DNA viruses can severely impact outcomes in paediatric immunocompromised patients. Current testing, which is generally limited to singleplex qPCR assays, can miss both common and rarer viruses if they are not targeted. Objectives: To evaluate the performance of the Galileo Viral Panel (Galileo), a sample-to-result shotgun metagenomics platform for the detection and quantification of 12 DNA viruses, compared to standard of care qPCR assays. Study design: A clinical performance evaluation was carried out using 43 prospectively collected EDTA plasma samples positive for one or more DNA viruses. Agreement between assays was assessed by overall, positive, and negative percent agreement, as well as quantitative agreement by linear regression and Bland-Altman analysis. Results: Overall positive percent agreement was 84% (95% CI: 76%-90%), and negative percent agreement was 95% (95% CI: 92%-97%). There was a high correlation between Galileo and qPCR for ADV, CMV, EBV, and VZV (R2 = 0.91) and a mean difference by Bland Altman of -0.43 log10 IU or cp/ml (95% limits of agreement, -1.37 to 0.51). In addition, there was a high correlation between Galileo Signal Score and qPCR for TTV (R2 = 0.85). Conclusion: We observed high qualitative and quantitative agreement between qPCR and Galileo. Galileo identified additional viruses that were not tested with routine qPCR and could impact clinical outcomes

    Perceptions of climate change and associated health impacts among communities in Johor River Basin, Malaysia

    Get PDF
    INTRODUCTION: As climate change is threatening every region of the world, extreme weather events resultant of global warming is occurring at increasing rate and scale in Malaysia. Weather-related disasters such as flood and haze pose critical challenges to the infrastructure and raise public health concerns in the country, especially when main economic sectors rely heavily on climate variability. Public perception on environmental issues is crucial for development of pro-environmental policies. Among studies conducted to understand public awareness regarding global warming, reports of perception on the health impacts were very limited. Taking this limitation into account, this study was designed to examine the perception on the health impacts of climate change among the diverse communities living in the Johor River Basin. MATERIALS AND METHODS: The cross-sectional study was conducted through cloud-data-based digital questionnaires completed by randomly selected residents in the Johor River Basin (n=647). Data was analysed with descriptive statistics using SPSS 27 (IBM\uae) Software. Comparisons between indigenous and non-indigenous communities were performed using Chi square analysis. RESULTS: Respondents in this study consisted of indigenous people (n=79) and non-indigenous people (n=568). Indigenous respondents generally perceived more frequent occurrence of extreme weather events in the next 20 years, even for the phenomena unfamiliar in Malaysian settings. All respondents showed similar concerns for health impacts of global warming, although the non-indigenous respondents perceived the risk further into the future (25 years) compared to the indigenous respondents who perceived current or imminent (<10 years) risks. Intense concerns for self, children, family members and community were shown by nearly all indigenous respondents (97-99%), while the non-indigenous people in this study expressed stronger concerns at country level and for future generations. During the last haze episode, most indigenous respondents (85%) did not notice any change in air quality nor discomfort among family members, in contrast 70% of the nonindigenous respondents claimed to have suffered from breathing problems themselves as well as others in the family. All respondents were concerned about air quality in their surroundings, indigenous people were concerned for the near future (<10 years), and non-indigenous people were concerned for the next 25 years. CONCLUSION: In this study, respondents were generally concerned about the health impacts of unimpeded global warming. There was significant difference in perceptions between indigenous and non-indigenous respondents. The findings were useful, complemented with further studies, to improve understanding of public awareness and to help develop relevant education programmes accessible for wider audience
    corecore